The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 27, 2015
Filed:
Mar. 18, 2013
Applicant:
Curis, Inc., Lexington, MA (US);
Inventors:
Xiong Cai, Bedford, MA (US);
Changgeng Qian, Wayland, MA (US);
Stephen Gould, San Carlos, CA (US);
Haixiao Zhai, Bedford, MA (US);
Assignee:
Curis, Inc., Lexington, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); C07D 419/12 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07D 419/14 (2006.01);
U.S. Cl.
CPC ...
C07D 419/12 (2013.01); A61K 31/506 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07D 419/14 (2013.01);
Abstract
The present invention relates to tyrosine kinase inhibitors that contain a zinc-binding moiety and their use in the treatment of tyrosine related diseases and disorders such as cancer. The said derivatives may further act as HDAC inhibitors.