The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 27, 2015

Filed:

Sep. 02, 2011
Applicants:

Kenneth W. Bair, Watertown, MA (US);

Timm Baumeister, Watertown, MA (US);

Alexandre J. Buckmelter, Watertown, MA (US);

Karl H. Clodfelter, Watertown, MA (US);

Bingsong Han, North Haven, CT (US);

Jian Lin, Acton, MA (US);

Dominic J. Reynolds, Stoneham, MA (US);

Chase C. Smith, Rutland, MA (US);

Zhongguo Wang, Watertown, MA (US);

Xiaozhang Zheng, Watertown, MA (US);

Inventors:

Kenneth W. Bair, Watertown, MA (US);

Timm Baumeister, Watertown, MA (US);

Alexandre J. Buckmelter, Watertown, MA (US);

Karl H. Clodfelter, Watertown, MA (US);

Bingsong Han, North Haven, CT (US);

Jian Lin, Acton, MA (US);

Dominic J. Reynolds, Stoneham, MA (US);

Chase C. Smith, Rutland, MA (US);

Zhongguo Wang, Watertown, MA (US);

Xiaozhang Zheng, Watertown, MA (US);

Assignee:

FORMA TM, LLC, Watertown, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/535 (2006.01); C07D 213/46 (2006.01); C07D 213/56 (2006.01); C07D 213/34 (2006.01); C07D 401/12 (2006.01); C07D 405/12 (2006.01); C07D 491/08 (2006.01); A61K 31/4406 (2006.01); A61K 31/4439 (2006.01); A61K 31/444 (2006.01); A61K 31/4709 (2006.01); A61K 31/5377 (2006.01); A61K 31/5386 (2006.01); A61K 45/06 (2006.01); C07D 401/14 (2006.01); C07D 451/04 (2006.01);
U.S. Cl.
CPC ...
C07D 213/56 (2013.01); A61K 31/444 (2013.01); A61K 31/4406 (2013.01); A61K 31/4439 (2013.01); A61K 31/4709 (2013.01); A61K 31/5377 (2013.01); A61K 31/5386 (2013.01); A61K 45/06 (2013.01); C07D 213/34 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 405/12 (2013.01); C07D 451/04 (2013.01); C07D 491/08 (2013.01);
Abstract

The present invention relates to compounds and composition for inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below.


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