The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 27, 2015
Filed:
Aug. 07, 2014
The United States of America, As Represented BY the Secretary, Department of Health and Human Service, Washington, DC (US);
The University of Birmingham, of Edgbaston, Birmingham, GB;
Jay A. Berzofsky, Bethesda, MD (US);
Jessica J. O'Konek, Ann Arbor, MI (US);
Masaki Terabe, Bethesda, MD (US);
Petr A. Illarionov, Birmingham, GB;
Gurdyal S. Besra, West Midlands, GB;
The United States of America, as represented by the Secretary, Department of Health and Human Services, Washington, DC (US);
The University of Birmingham, Edgbaston, Birmingham, GB;
Abstract
β-mannosylceramides or salts or solvates thereof in a pharmaceutically acceptable carrier, for use as a Type I NKT cell agonist in conjunction with a therapeutically effective amount of α-galactosylceramide or a salt or a solvate thereof, and/or at least one or more T-cell co-stimulatory molecules, disclosed. Compositions comprising β-mannosylceramide, as well as methods of treatment of tumors are also provided.