logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9165703 B1

PDFFull Text
Expired
Date of Patent:
Oct. 20, 2015

Filed:

Dec. 21, 2011

Methods and systems for prolonged localization of drug delivery

Applicants:

Bryan Laulicht, Great Neck, NY (US);

Edith Mathiowitz, Brookline, MA (US);

Inventors:

Bryan Laulicht, Great Neck, NY (US);

Edith Mathiowitz, Brookline, MA (US);

Assignee:

BROWN UNIVERSITY, Providence, RI (US);

Attorneys:

Lawson & Weitzen LLP

Sonia K. Guterman

Preeti T. Arun

Primary Examiner:

Rachael E Bredefeld

Assistant Examiner:

Dominic Lazaro

Int. Cl.
CPC ...
A61M 37/00 (2006.01); A61B 18/00 (2006.01); A61B 6/00 (2006.01); A61N 5/00 (2006.01); H01F 7/00 (2006.01); B29B 9/00 (2006.01); H01F 1/00 (2006.01); A61K 9/50 (2006.01); A61B 5/06 (2006.01); A61B 6/12 (2006.01); A61J 3/10 (2006.01); A61J 3/07 (2006.01);
U.S. Cl.
CPC ...
H01F 1/0054 (2013.01); A61B 5/062 (2013.01); A61B 6/12 (2013.01); A61J 3/10 (2013.01); A61K 9/501 (2013.01); A61K 9/5031 (2013.01); A61K 9/5036 (2013.01); A61K 9/5057 (2013.01); A61K 9/5094 (2013.01); A61J 3/071 (2013.01);
Abstract

An effective method for prolonging localization of therapeutics within the rat gastrointestinal tract of at least about 12 hours is provided. The method includes localization of therapeutic agents that are nanoparticulated or nanoencapsulated. Attractive forces between an orally administered magnetic dose and an external magnet were monitored and internal dose motion in real time using biplanar videofluoroscopy was visualized. Tissue elasticity was quantified as a measure of tissue health by combining data streams. The methods address safety, efficacy, and monitoring capacity of magnetically localized doses and show a platform for testing the benefits of localized drug delivery.

Find Patent Forward Citations

Quick Actions:

Laulicht, Bryan. (2015). Methods and systems for prolonged localization of drug delivery (U.S. Patent No. 9165703). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9165703

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…