The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 20, 2015
Filed:
Sep. 10, 2010
Christian Albers, Bremen, DE;
Eckhard Belau, Lilienthal, DE;
Sören-oliver Deininger, Leipzig, DE;
Sandra Rauser, Munich, DE;
Detlev Suckau, Grasberg, DE;
Axel Walch, Baldham, DE;
Christian Albers, Bremen, DE;
Eckhard Belau, Lilienthal, DE;
Sören-Oliver Deininger, Leipzig, DE;
Sandra Rauser, Munich, DE;
Detlev Suckau, Grasberg, DE;
Axel Walch, Baldham, DE;
Bruker Daltonik GmbH, Bremen, DE;
Abstract
A method for determining an expression of human epidermal growth factor receptor 2 (HER2) of a subject. The method includes providing a sample from the subject; measuring one of (i) amounts of two or more proteins in the sample, each protein having a molecular weight substantially equal to 4740, 8404, 8419, 8435, 8450, 8455, 8465, 8570, 8607 or 8626 atomic mass units, and (ii) amounts of at least one of human cystein-rich intestinal protein 1 (CRIP1), one or more variants of the human cystein-rich intestinal protein 1 (CRIP1 variants), and proteolytic digestion products thereof in the sample; and comparing the amounts of the proteins to control amounts, which control amounts are determinative of the expression of the human epidermal growth factor receptor 2.