The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 20, 2015

Filed:

Mar. 08, 2011
Applicants:

Sumio Sugano, Minato-ku, JP;

Yukari Kanzaki, Minato-ku, JP;

Tsuneo Saga, Chiba, JP;

Atsushi Tsuji, Chiba, JP;

Inventors:

Sumio Sugano, Minato-ku, JP;

Yukari Kanzaki, Minato-ku, JP;

Tsuneo Saga, Chiba, JP;

Atsushi Tsuji, Chiba, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/574 (2006.01); A61K 51/10 (2006.01); C07K 16/30 (2006.01); C07K 16/18 (2006.01); C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/574 (2013.01); A61K 51/1045 (2013.01); C07K 16/18 (2013.01); C07K 16/30 (2013.01); G01N 2800/00 (2013.01);
Abstract

[PROBLEM] To provide a monoclonal antibody against a biomarker which shows high specificity and can be effectively used in detection and diagnosis of various lesions relevant to various kinds of carcinomas and foci of necrosis, and so forth. [MEANS] A monoclonal antibody against a necrosis marker consisting the following amino acid sequence: (1) the amino acid sequence of SEQ ID NO: 1, or (2) an amino acid sequence having substitution, deletion and/or insertion of one or several amino acid residues in the amino acid sequence of (1) or sharing a homology of 90% or more with the amino acid sequence of (1), and showing the same function, activity or property as that of the amino acid sequence of (1) as a protein.


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