The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 20, 2015

Filed:

Mar. 26, 2013
Applicant:

Technische Universität München, Munich, DE;

Inventors:

Ulrich Rant, Munich, DE;

Wolfgang Kaiser, Munich, DE;

Paul Andreas Hampel, Fischbachau, DE;

Jens Niemax, Munich, DE;

Andreas Langer, Munich, DE;

Jelena Knezevic, Munich, DE;

Assignee:

Dynamic Biosensors GmbH, Martinsried/Planegg, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/327 (2006.01); G01N 21/64 (2006.01); G01N 33/543 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
G01N 27/327 (2013.01); C12Q 1/6825 (2013.01); G01N 21/6408 (2013.01); G01N 21/6458 (2013.01); G01N 33/5438 (2013.01); C12Q 1/6823 (2013.01); G01N 2021/6432 (2013.01);
Abstract

Arrangements are described for evaluating characteristics of target molecules. A biochip is received which includes a substrate to which charged probe molecules are attached. The probe molecules have a marker to allow generating signals indicative of the distance of a portion of the probe molecule from the substrate. The signals are detected and means for an external electric field is generated to which the probe molecules are exposed. A control means acts to: (A) apply an external electric field causing the portion of the probe molecule to approach the substrate, and (B) apply an external electric field causing the portion of the probe molecule to move away from the substrate. The signal is recorded as a function of time during step (A) and/or step (B). Steps (A) and (B) are repeated for a predetermined number of times and the recorded signals are combined.


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