The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 20, 2015
Filed:
Apr. 30, 2013
Vivian Choi, Waltham, MA (US);
Chad Eric Bigelow, Somerville, MA (US);
Thaddeus Peter Dryja, Milton, MA (US);
Seshidhar Reddy Police, Burlington, MA (US);
Vivian Choi, Waltham, MA (US);
Chad Eric Bigelow, Somerville, MA (US);
Thaddeus Peter Dryja, Milton, MA (US);
Seshidhar Reddy Police, Burlington, MA (US);
Novartis AG, Basel, CH;
Abstract
The present invention relates to viral vectors that are capable of delivering a heterologous gene to the retina and in particular delivering RLBP1 to RPE and Müller cells of the retina. The invention also relates nucleic acids useful for producing viral vectors, compositions comprising the viral vectors and uses of the compositions and viral vectors. The invention also relates to methods of delivering and/or expressing a heterologous gene to the retina, improving the rate of dark adaption in a subject and treating RLBP1-associated retinal dystrophy.