The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 20, 2015

Filed:

Jan. 10, 2013
Applicant:

Noxxon Pharma Ag, Berlin, DE;

Inventors:

Simone Schulzchen, Berlin, DE;

Werner Purschke, Berlin, DE;

Florian Jarosch, Berlin, DE;

Kai Hohlig, Berlin, DE;

Christian Maasch, Berlin, DE;

Sven Klussmann, Berlin, DE;

Assignee:

NOXXON Pharma AG, Berlin, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01); A61K 48/00 (2006.01); C12N 15/115 (2010.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
C12N 15/115 (2013.01); C12Q 1/6876 (2013.01); C12N 2310/16 (2013.01); C12N 2310/344 (2013.01); C12N 2310/351 (2013.01); C12N 2320/10 (2013.01); C12N 2320/30 (2013.01);
Abstract

The present invention is related to a nucleic acid molecule capable of binding to CGRP, wherein the nucleic acid molecule comprises a central stretch of nucleotides, wherein the central stretch of nucleotides comprises a nucleotide sequence of 5' HWnnYGGAnAnUMnnYnnnnnKnRnADnnARnUnCnnUnn3′ [SEQ ID NO: 99], wherein H, W, Y, G, A, U, M, B, K, R, D, C are ribonucleotides, and nis R or dG, nis U or dT, nis K or dG, nis C or dC, nis M or dC, nis B or dU, nis N or dG, nis Y or dT, nis N or dC, nis R or dG, nis V or dA, nis K or dT or dU, nis G or dG, nis A or dA, nis U or dT, nis R or dG, nis Y or dC, nis C or dC, nis B or dC, nis C or dC, nis C or dC, and dG, dT, dC, dA and dU are 2′-deoxyribonucleotides.


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