The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 20, 2015

Filed:

Nov. 13, 2007
Applicants:

Takashi Matsui, Kanagawa, JP;

Takashi Muramatsu, Aichi, JP;

Masatoshi Hayashibara, Tokyo, JP;

Takanori Ito, Kanagawa, JP;

Tsukasa Uno, Yokohama, JP;

Sadatoshi Sakuma, Kanagawa, JP;

Inventors:

Takashi Matsui, Kanagawa, JP;

Takashi Muramatsu, Aichi, JP;

Masatoshi Hayashibara, Tokyo, JP;

Takanori Ito, Kanagawa, JP;

Tsukasa Uno, Yokohama, JP;

Sadatoshi Sakuma, Kanagawa, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/22 (2006.01); G01N 33/68 (2006.01); A61K 39/395 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/22 (2013.01); A61K 39/3955 (2013.01); G01N 33/6854 (2013.01); G01N 33/6857 (2013.01); A61K 2039/505 (2013.01); C07K 2316/96 (2013.01); C07K 2317/565 (2013.01);
Abstract

It is intended to provide an antibody which inhibits the function of midkine. An antibody which recognizes an epitope consisting of amino acid residues 62 to 104 of midkine or a fragment thereof; DNA encoding the antibody or a fragment thereof; a recombinant vector which contains the DNA; a transformant which has the vector or a hybridoma which produces the antibody; a method for producing the antibody by allowing the transformant or hybridoma to produce the antibody or a fragment thereof and collecting the resulting antibody or fragment thereof; a pharmaceutical composition containing the antibody or a fragment thereof as an active ingredient; and a diagnostic agent containing the antibody or a fragment thereof as an active ingredient.


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