The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 20, 2015
Filed:
Apr. 19, 2012
Walter Anton Blättler, Brookline, MA (US);
Carlos J. R. C. Romão, Cascais, PT;
Sandra Sofia Pereira Rodrigues, Moscavide - Lisboa, PT;
Lukas Adrian Kromer, Winterthur, CH;
Leo Edmond Otterbein, Beverly, MA (US);
David John Gallo, Salem, MA (US);
Walter Anton Blättler, Brookline, MA (US);
Carlos J. R. C. Romão, Cascais, PT;
Sandra Sofia Pereira Rodrigues, Moscavide - Lisboa, PT;
Lukas Adrian Kromer, Winterthur, CH;
Leo Edmond Otterbein, Beverly, MA (US);
David John Gallo, Salem, MA (US);
Alfama, Inc., Cambridge, MA (US);
Abstract
Provided herein are novel carbon-monoxide releasing molecules (CO-RMs) of the Formula (I): and esters, amides, salts, solvates and hydrates thereof; wherein Rand Rare as described herein. Also provided are pharmaceutical compositions comprising these compounds, methods of their preparation, and their use in the treatment of liver disease and inflammation.