The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 20, 2015
Filed:
Dec. 12, 2014
Vertex Pharmaceuticals Incorporated, Boston, MA (US);
Corey Anderson, San Diego, CA (US);
Sara Sabina Hadida-Ruah, LaJolla, CA (US);
Julian Marian Charles Golec, Abingdon, GB;
Beili Zhang, San Diego, CA (US);
Benjamin Joseph Littler, Carlsbad, CA (US);
Ali Keshavarz-Shokri, San Diego, CA (US);
Tim Edward Alacio, San Diego, CA (US);
Daniel T. Belmont, Grafton, MA (US);
VERTEX PHARMACEUTICALS INCORPORATED, Boston, MA (US);
Abstract
The invention relates to prodrug compounds of formula I: wherein R, R, R, Rand X are as defined herein. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders, including pain. The compounds of formula I possess advantageous solubility and physicochemical properties.