The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 20, 2015

Filed:

May. 02, 2013
Applicant:

Southern Research Institute, Birmingham, AL (US);

Inventor:

Subramaniam Ananthan, Birmingham, AL (US);

Assignee:

Southern Research Institute, Birmingham, AL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/485 (2006.01); C07D 489/08 (2006.01); C07D 491/18 (2006.01); C07D 489/02 (2006.01); C07D 489/06 (2006.01);
U.S. Cl.
CPC ...
C07D 491/18 (2013.01); C07D 489/02 (2013.01); C07D 489/06 (2013.01); C07D 489/08 (2013.01);
Abstract

Provided are compounds of the formula: R; R, R; R; A; X; Y and Z are defined in the present disclosure; pharmaceutically acceptable salts thereof, deuterium forms thereof, isomers thereof, and mixture thereof; and processes for their preparation. The compounds can be used for treating a patient suffering from a condition that is capable of treatment with an agonist and/or antagonist of the opioid receptors and are especially useful a patient suffering from pain, treating a patient in need of an immunosuppressant to prevent rejection in organ transplant and skin graft, in need of an anti-allergic agent, in need of an anti-inflammatory agent, in need of a brain cell protectant, for drug and/or alcohol abuse, to decrease gastric secretion, for diarrhea, for cardiovascular disease, for a respiratory disease, in need of a cough and/or respiratory depressant, for mental illness, for epileptic seizures and other neurologic disorders.


Find Patent Forward Citations

Loading…