The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 20, 2015

Filed:

Dec. 20, 2013
Applicant:

Abbvie Inc., North Chicago, IL (US);

Inventors:

Irini Akritopoulou-Zanze, Libertyville, IL (US);

Brian D. Wakefield, Vernon Hills, IL (US);

Helmut Mack, Ludwigshafen, DE;

Sean C. Turner, Mannheim, DE;

Alan F. Gasiecki, Vernon Hills, IL (US);

Vijaya J. Gracias, West Newton, MA (US);

Kathy A. Sarris, Mundelein, IL (US);

Douglas M. Kalvin, Buffalo Grove, IL (US);

Melissa J. Michmerhuizen, Beach Park, IL (US);

Qi Shuai, Dekalb, IL (US);

Jyoti R. Patel, Libertyville, IL (US);

Margaretha H. M. Bakker, Seeheim-Jugenheim, DE;

Nicole Teusch, Cologne, DE;

Eric F. Johnson, Antioch, IL (US);

Peter J. Kovar, Chicago, IL (US);

Stevan W. Djuric, Libertyville, IL (US);

Andrew J. Long, Chelmsford, MA (US);

Anil Vasudevan, Union Grove, WI (US);

Dawn M. George, Charlton, MA (US);

Lu Wang, Westborough, MA (US);

Biqin Li, Southborough, MA (US);

Nigel S. Moore, Shrewsbury, MA (US);

Adrian D. Hobson, Shrewsbury, MA (US);

Keith W. Woods, Lincolnshire, IL (US);

Julie M. Miyashiro, Morton Grove, IL (US);

Steven L. Swann, Jr., San Diego, CA (US);

Thomas D. Penning, Elmhurst, IL (US);

Assignee:

AbbVie Inc., North Chicago, IL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/04 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 403/14 (2006.01); C07D 405/04 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); C07D 413/14 (2006.01); C07D 417/04 (2006.01); C07D 417/14 (2006.01); C07D 513/04 (2006.01);
U.S. Cl.
CPC ...
C07D 413/04 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/14 (2013.01); C07D 405/04 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01); C07D 417/04 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 513/04 (2013.01);
Abstract

The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, wherein A, R, R, Rand m, are defined in the description. The present invention relates also to methods of making said compounds, and compositions containing said compounds which are useful for inhibiting kinases such as Glycogen Synthase kinase 3 (GSK-3), Rho kinase (ROCK), Janus Kinases (JAK), Cdc7, AKT, PAK4, PLK, CK2, KDR, MK2, JNK1, aurora, pim 1 and nek 2.


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