The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 20, 2015
Filed:
Jun. 27, 2014
Applicant:
Pharmacyclics Llc, Sunnyvale, CA (US);
Inventors:
Aleksandr Kolesnikov, San Francisco, CA (US);
Roopa Rai, San Carlos, CA (US);
William Dvorak Shrader, Belmont, CA (US);
Steven M. Torkelson, San Mateo, CA (US);
Kieron E. Wesson, Burlingame, CA (US);
Wendy B. Young, San Mateo, CA (US);
Assignee:
PHARMACYCLICS LLC, Sunnyvale, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 235/18 (2006.01); C07D 401/12 (2006.01); C07D 403/10 (2006.01); C07D 235/12 (2006.01); C07D 235/16 (2006.01); C07F 9/09 (2006.01); C07F 9/12 (2006.01); C07F 9/6512 (2006.01); C12Q 1/56 (2006.01);
U.S. Cl.
CPC ...
C07D 235/18 (2013.01); C07D 235/12 (2013.01); C07D 235/16 (2013.01); C07D 401/12 (2013.01); C07D 403/10 (2013.01); C07F 9/094 (2013.01); C07F 9/12 (2013.01); C07F 9/65128 (2013.01); C12Q 1/56 (2013.01);
Abstract
The present invention relates to novel inhibitors of Factors VIIa, IXa, Xa, XIa, in particular Factor VIIa, pharmaceutical compositions comprising these inhibitors, and methods for using these inhibitors for treating or preventing thromboembolic disorders, cancer or rheumatoid arthritis. Processes for preparing these inhibitors are also disclosed.