The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 20, 2015
Filed:
May. 12, 2014
Applicants:
Northwestern University, Evanston, IL (US);
Cambria Pharmaceuticals, Inc., Cambridge, MA (US);
Inventors:
Donald Kirsch, Bedford, MA (US);
Radhia Benmohamed, Tewksbury, MA (US);
Anthony C. Arvanites, Medford, MA (US);
Richard I. Morimoto, Evanston, IL (US);
Wei Zhang, Evanston, IL (US);
Richard B. Silverman, Winnetka, IL (US);
Assignees:
Northwestern University, Evanston, IL (US);
Cambria Pharmaceuticals, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 49/00 (2006.01); C07D 295/205 (2006.01); C07C 69/00 (2006.01); C07C 69/75 (2006.01); C07C 49/563 (2006.01); C07C 49/567 (2006.01); C07C 49/577 (2006.01); A61K 31/136 (2006.01); A61K 31/495 (2006.01);
U.S. Cl.
CPC ...
C07C 69/75 (2013.01); C07C 49/563 (2013.01); C07C 49/567 (2013.01); C07C 49/577 (2013.01);
Abstract
The present invention relates to the identification of provided cyclohexane-1,3-diones (CHD compounds) and pharmaceutical compositions thereof for treating subjects with amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. The invention also provides methods of preparing the provided CHD compounds.