The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 20, 2015

Filed:

Jun. 24, 2014
Applicant:

Fziomed, Inc., San Luis Obispo, CA (US);

Inventors:

Samuel J. Falcone, Morro Bay, CA (US);

Richard A. Berg, Arroyo Grande, CA (US);

Assignee:

FzioMed, Inc., San Luis Obispo, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/48 (2006.01); A61F 2/44 (2006.01); A61L 27/20 (2006.01); A61L 27/50 (2006.01); A61L 27/54 (2006.01); A61L 31/04 (2006.01); A61L 31/14 (2006.01); A61L 31/16 (2006.01); C08B 11/20 (2006.01); C08L 1/28 (2006.01); A61F 2/30 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48215 (2013.01); A61F 2/441 (2013.01); A61L 27/20 (2013.01); A61L 27/50 (2013.01); A61L 27/54 (2013.01); A61L 31/042 (2013.01); A61L 31/14 (2013.01); A61L 31/16 (2013.01); C08B 11/20 (2013.01); C08L 1/286 (2013.01); A61F 2002/30062 (2013.01); A61F 2002/3068 (2013.01); A61F 2002/30224 (2013.01); A61F 2002/30242 (2013.01); A61F 2002/30581 (2013.01); A61F 2002/30677 (2013.01); A61F 2002/444 (2013.01); A61F 2002/448 (2013.01); A61F 2002/4435 (2013.01); A61F 2210/0004 (2013.01); A61F 2230/0071 (2013.01); A61F 2250/0068 (2013.01); A61L 2430/02 (2013.01); Y10T 428/2982 (2015.01);
Abstract

Compositions comprising carboxypolysaccharides (CPS) including carboxymethyl cellulose (CMC) and polyethylene glycols (PEGs) are provided where the PEG is a PEG-epoxide covalently linked to the CPS. In certain embodiments, the PEG attaches to only one CPS, forming a decorated CPS. In other embodiments, bi-functional PEG molecules are attached to adjacent CPSs, thereby forming a covalently cross-linked composition. Additional embodiments include PEG/CMC compositions where the PEG is a multi-branch PEG and/or a multi-arm PEG. PEG/CMC compositions can be made with desired viscoelastic properties, and such compositions can be used as space-filling materials, load-bearing materials, anti-adhesion compositions, drug delivery vehicles or lubrication of tissues and medical instruments.


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