The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 20, 2015
Filed:
Jul. 08, 2011
Guangmei Yan, Guangzhou, CN;
Halyan HU, Guangzhou, CN;
Jingxia Zhang, Guangzhou, CN;
Pengxin Qiu, Guangzhou, CN;
Ling LI, Guangzhou, CN;
Ning Tian, Guangzhou, CN;
Guangmei Yan, Guangzhou, CN;
Halyan Hu, Guangzhou, CN;
Jingxia Zhang, Guangzhou, CN;
Pengxin Qiu, Guangzhou, CN;
Ling Li, Guangzhou, CN;
Ning Tian, Guangzhou, CN;
Guangzhou Cellprotek Pharmaceutical Ltd., Guangzhou, CN;
Abstract
A 5α-androstane-3β,5,6β-triol injection and its preparation are disclosed. The injection uses hydroxypropyl-β-cyclodextrin as a solubilizing agent and the active ingredient is present at a weight ratio of 1-20:40-500 to the hydroxypropyl-β-cyclodextrin. The injection may also comprise, by weight, 1-100 parts of at least one isotonic adjusting agent, 0-200 parts of at least one freeze drying filler, and 0-2000 parts of at least one solvent. The preparation method comprises dissolving hydroxypropyl-β-cyclodextrin solution, 5α-androstane-3β,5,6β-triol and at least one additional soluble excipient in water for injection in sequence to obtain a raw injection solution, and subjecting the raw injection solution to decolorization, depyrogenation, filtration and sterilization to obtain the injection, Drying the filtrate yields a solid for injection.