The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 20, 2015
Filed:
Oct. 16, 2014
Applicant:
Pozen Inc., Chapel Hill, NC (US);
Inventor:
John R. Plachetka, Chapel Hill, NC (US);
Assignee:
Pozen Inc., Chapel Hill, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/24 (2006.01); A61K 9/28 (2006.01); A61K 9/16 (2006.01); A61K 9/50 (2006.01); A61K 31/192 (2006.01); A61K 31/495 (2006.01); A61K 45/06 (2006.01); A61K 9/48 (2006.01); A61K 31/426 (2006.01); A61K 31/4439 (2006.01); A61K 9/20 (2006.01);
U.S. Cl.
CPC ...
A61K 9/209 (2013.01); A61K 9/1611 (2013.01); A61K 9/2095 (2013.01); A61K 9/28 (2013.01); A61K 9/4891 (2013.01); A61K 9/5026 (2013.01); A61K 9/5073 (2013.01); A61K 9/5084 (2013.01); A61K 9/5089 (2013.01); A61K 31/192 (2013.01); A61K 31/426 (2013.01); A61K 31/4439 (2013.01); A61K 31/495 (2013.01); A61K 45/06 (2013.01); A61K 9/2846 (2013.01); A61K 9/2866 (2013.01);
Abstract
The present invention is directed to drug dosage forms that release an agent that raises the pH of a patient's gastrointestinal tract, followed by a non-steroidal anti-inflammatory drug. The dosage form is designed so that the NSAID is not released until the intragastric pH has been raised to a safe level. The invention also encompasses methods of treating patients by administering this coordinated release, gastroprotective, antiarthritic/analgesic combination unit dosage form to achieve pain and symptom relief with a reduced risk of developing gastrointestinal damage such as ulcers, erosions and hemorrhages.