The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 13, 2015

Filed:

Dec. 20, 2011
Applicants:

Arezou Zargari, Solna, SE;

Nicolai Kouznetzov, Järfälla, SE;

Charlotte Admyre, Vendelsö, SE;

Petra Von Stein, Upplands Väsby, SE;

Oliver Von Stein, Upplands Väsby, SE;

Inventors:

Arezou Zargari, Solna, SE;

Nicolai Kouznetzov, Järfälla, SE;

Charlotte Admyre, Vendelsö, SE;

Petra Von Stein, Upplands Väsby, SE;

Oliver Von Stein, Upplands Väsby, SE;

Assignee:

INDEX PHARMACEUTICALS AB, Stockholm, SE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 19/00 (2006.01); C12P 19/34 (2006.01); G01N 33/68 (2006.01); C12N 15/117 (2010.01);
U.S. Cl.
CPC ...
G01N 33/6869 (2013.01); C12N 15/117 (2013.01); G01N 33/6866 (2013.01); C12N 2310/17 (2013.01); C12N 2320/11 (2013.01);
Abstract

The present invention relates to methods of identifying oligonucleotides capable of modulating the immune system in a mammalian subject, comprising analysis of which tertiary structural type said oligonucleotide adopts, in phosphate-buffered saline solution. Further, the invention provides oligonucleotides identifiable by the methods of the invention and to their use in methods of treating diseases, such as inflammatory diseases, autoimmune diseases, infectious diseases, neurodegenerative diseases and cancer.


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