The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 13, 2015

Filed:

May. 31, 2010
Applicants:

John D. Brennan, Dundas, CA;

Carlos Filipe, Ancaster, CA;

Zakir Hossain, Hamilton, CA;

Roger Luckham, Hamilton, CA;

Anne Marie Smith, Ancaster, CA;

Julie Marie Lebert, London, CA;

Robert Pelton, Ancaster, CA;

Inventors:

John D. Brennan, Dundas, CA;

Carlos Filipe, Ancaster, CA;

Zakir Hossain, Hamilton, CA;

Roger Luckham, Hamilton, CA;

Anne Marie Smith, Ancaster, CA;

Julie Marie Lebert, London, CA;

Robert Pelton, Ancaster, CA;

Assignee:

McMaster University, Hamilton, Ontario, CA;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/00 (2006.01); C12Q 1/46 (2006.01); G01N 33/543 (2006.01); G01N 33/548 (2006.01); G01N 33/552 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/001 (2013.01); C12Q 1/46 (2013.01); G01N 33/548 (2013.01); G01N 33/5436 (2013.01); G01N 33/552 (2013.01);
Abstract

Novel solid-phase biosensors that utilize ink jet printing of biocompatible sol-gel based inks to create sensor strips are reported herein. Biomolecules and other reagents useful in bioassays to detect, for example, pathogenic microorganisms or toxic substances, are immobilized on a substrate, which can be paper based, by layering these substances between two layers of biomolecule compatible sol gel. The sol gel precursor solutions and solutions of the assay reagents are printed from separate nozzles in a layered approach which avoids clogging of the nozzles by the pre-mature gelling of the sol gel precursor solution. In certain embodiments of the application, a capture agent is used to concentrate a compound to be detected in specific areas on the substrate to facilitate detection.


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