The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 13, 2015

Filed:

Apr. 18, 2008
Applicants:

Gayane Buniatian, Tubingen, DE;

Rolf Gebhardt, Leipzig, DE;

Christoph Gleiter, Tubingen, DE;

Lusine Danielyan, Tubingen, DE;

Barbara Proksch, Tubingen, DE;

Inventors:

Gayane Buniatian, Tubingen, DE;

Rolf Gebhardt, Leipzig, DE;

Christoph Gleiter, Tubingen, DE;

Lusine Danielyan, Tubingen, DE;

Barbara Proksch, Tubingen, DE;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 63/00 (2006.01); C12N 5/079 (2010.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
C12N 5/0622 (2013.01); A61K 35/12 (2013.01); C12N 2502/14 (2013.01);
Abstract

The present invention relates to a method for the treatment of organs which are degenerative and/or in the pathological state by means of the use of cells, which are phenotypically stably differentiating or differentiated but not necessarily ultimately predetermined with respect to development, from a donor organ selected according to the principles of the opposite cell differentiation program (OCDP) and also to the use of cells of this type for the treatment or for the production of a drug for treatment of the same. Furthermore, the present invention relates to pharmaceutical agents comprising suitable phenotypically stable cells, cells of a first organ which is different from the second organ with respect to organ type thereby being used, which, in the normal physiological state with respect to a predetermined set of expressed genes and/or phenotypical properties, have opposite properties to the second cells in the normal physiological state.


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