The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 13, 2015

Filed:

Jul. 17, 2012
Applicants:

Shu-chen LU, Thousand Oaks, CA (US);

Minghan Wang, Newbury Park, CA (US);

Inventors:

Shu-Chen Lu, Thousand Oaks, CA (US);

Minghan Wang, Newbury Park, CA (US);

Assignee:

AMGEN INC., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01); A61P 35/00 (2006.01); A61K 39/395 (2006.01); A61P 27/02 (2006.01); G01N 33/53 (2006.01); C12P 21/02 (2006.01); C12N 15/09 (2006.01); C12N 15/11 (2006.01); C12N 15/13 (2006.01); C07H 21/02 (2006.01); C07K 16/26 (2006.01); G01N 33/74 (2006.01); C07K 14/47 (2006.01); C07K 14/515 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/26 (2013.01); A61K 39/3955 (2013.01); C07H 21/02 (2013.01); C07K 16/18 (2013.01); C12N 15/09 (2013.01); C12N 15/11 (2013.01); C12P 21/02 (2013.01); G01N 33/53 (2013.01); G01N 33/74 (2013.01); A61K 2039/505 (2013.01); C07K 14/515 (2013.01); C07K 2317/34 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); G01N 2800/7014 (2013.01);
Abstract

This disclosure relates to apelin antigen-binding proteins and methods of using the apelin antigen-binding proteins. The antigen-binding protein may comprise an antibody to apelin and can be used to treat pathological conditions involving angiogenesis. The pathological conditions can comprise cancer or retinopathy and/or retinopathy-related complications.


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