The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 13, 2015
Filed:
Jun. 06, 2013
Applicant:
Alkermes, Inc., Waltham, MA (US);
Inventors:
Juan Alvarez, Chelmsford, MA (US);
Jean Chamoun, Waltham, MA (US);
Heather C. Losey, Lexington, MA (US);
Assignee:
Alkermes, Inc., Waltham, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); C07K 14/545 (2006.01); C07K 14/54 (2006.01); C07K 14/55 (2006.01); C07K 14/715 (2006.01); C07K 14/50 (2006.01); C07K 14/705 (2006.01); C07K 14/71 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4713 (2013.01); C07K 14/4727 (2013.01); C07K 14/50 (2013.01); C07K 14/545 (2013.01); C07K 14/5412 (2013.01); C07K 14/5443 (2013.01); C07K 14/55 (2013.01); C07K 14/70503 (2013.01); C07K 14/71 (2013.01); C07K 14/7155 (2013.01); C07K 2319/00 (2013.01); C07K 2319/02 (2013.01);
Abstract
The present invention provides fusion proteins comprising a mucin-domain polypeptide covalently linked to an active protein that has improved properties (e.g. pharmacokinetic and/or physicochemical properties) compared to the same active protein not linked to mucin-domain polypeptide, as well as methods for making and using the fusion proteins of the invention.