The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 13, 2015
Filed:
Mar. 11, 2014
Applicant:
Janssen Pharmaceutica NV, Beerse, BE;
Inventors:
Philip Pye, Beerse, BE;
Cyril Ben Haim, Beerse, BE;
Matteo Conza, Schaffhausen, CH;
Ioannis Nicolaos Houpis, Antwerp, BE;
Assignee:
Janssen Pharmaceutica NV, Beerse, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 401/04 (2006.01); A61K 31/519 (2006.01); C07D 211/56 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07D 211/56 (2013.01); C07D 401/04 (2013.01);
Abstract
Disclosed is a process for the preparation of the following compounds: where R, Rand Rhave the definitions in the description, as well as a process to prepare other intermediates that may be useful to synthesize downstream products, especially compounds that are useful as medicaments, for instance Bruton's tyrosine kinase (Btk) inhibitors such as ibrutinib. Also disclosed are other processes, other intermediates and compounds per se.