The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 13, 2015
Filed:
Aug. 28, 2013
Applicant:
Janssen Sciences Ireland Uc, Little Island, Co Cork, IE;
Inventors:
Koen Vandyck, Paal-Beringen, BE;
Wim Gaston Verschueren, Berchem, BE;
Pierre Jean-Marie Bernard Raboisson, Rosieres, BE;
Assignee:
JANSSEN SCIENCES IRELAND UC, Little Island, Co Cork, IE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 231/56 (2006.01); C07D 261/20 (2006.01); A61K 31/416 (2006.01); C07D 471/04 (2006.01); A61K 31/423 (2006.01); C07D 405/12 (2006.01); A61K 31/437 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/416 (2013.01); A61K 31/423 (2013.01); A61K 31/437 (2013.01); A61K 45/06 (2013.01); C07D 231/56 (2013.01); C07D 261/20 (2013.01); C07D 405/12 (2013.01);
Abstract
Inhibitors of HBV replication of Formula (I) including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein A-E, R, R, Rand R, have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy.