The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 13, 2015

Filed:

Jul. 27, 2012
Applicants:

Satoshi Yamamoto, Kanagawa, JP;

Junya Shirai, Kanagawa, JP;

Atsuko Ochida, Kanagawa, JP;

Yoshiyuki Fukase, Kanagawa, JP;

Yoshihide Tomata, Kanagawa, JP;

Ayumu Sato, Kanagawa, JP;

Shotaro Miura, Kanagawa, JP;

Kazuko Yonemori, Kanagawa, JP;

Ryokichi Koyama, Kanagawa, JP;

Inventors:

Satoshi Yamamoto, Kanagawa, JP;

Junya Shirai, Kanagawa, JP;

Atsuko Ochida, Kanagawa, JP;

Yoshiyuki Fukase, Kanagawa, JP;

Yoshihide Tomata, Kanagawa, JP;

Ayumu Sato, Kanagawa, JP;

Shotaro Miura, Kanagawa, JP;

Kazuko Yonemori, Kanagawa, JP;

Ryokichi Koyama, Kanagawa, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 277/30 (2006.01); C07D 277/56 (2006.01); C07D 211/90 (2006.01); C07D 417/12 (2006.01); C07D 471/04 (2006.01); C07D 401/12 (2006.01); C07D 277/24 (2006.01); C07D 401/04 (2006.01); C07D 417/04 (2006.01); C07D 417/14 (2006.01); C07D 491/107 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 417/04 (2013.01); C07D 417/14 (2013.01); C07D 491/107 (2013.01);
Abstract

A heterocyclic compound having an RORγt inhibitory activity, which is a compound of formula (I) or a salt thereof is provided. The compound has ring A, which is an optionally substituted cyclic group and is bound to a pyrazole ring though Q. Q is a bond, optionally substituted Calkylene, optionally substituted Calkenylene, or optionally substituted Calkynylene. Ris a substituent. Ring B is a thiazole ring, an isothiazole ring or a dihydrothiazole ring, each of which is optionally further substituted by a substituent in addition to R. Ris an optionally substituted cyclyl-carbonyl-Calkyl group, an optionally substituted aminocarbonyl-Calkyl group, an optionally substituted cyclyl-Calkyl group, an optionally substituted cyclyl-Calkylamino-carbonyl group, an optionally substituted aminocarbonyl-Calkenyl group, an optionally substituted Calkylcarbonylamino-Calkyl group, an optionally substituted cyclyl-aminocarbonyl group, an optionally substituted cyclyl-carbonyl group or an optionally substituted non-aromatic heterocyclic group.


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