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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9156826 B1

PDFFull Text
Date of Patent:
Oct. 13, 2015

Filed:

Jun. 28, 2013

Asymmetrical reversible neuromuscular blocking agents of ultra-short, short, or intermediate duration

Applicant:

Cornell University, Ithaca, NY (US);

Inventors:

John J. Savarese, Southbury, CT (US);

Jeff D. McGilvra, Belgium, WI (US);

Assignee:

Cornell University, Ithaca, NY (US);

Attorney:

Schwegman Lundberg & Woessner, P.A.

Primary Examiner:

Zinna Northington Davis

Int. Cl.
CPC ...
C07D 401/12 (2006.01); A61K 31/4725 (2006.01); C07D 405/12 (2006.01); C07D 217/20 (2006.01); A61K 31/5377 (2006.01); C07D 405/10 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 405/12 (2013.01); A61K 31/4725 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); C07D 217/20 (2013.01); C07D 401/12 (2013.01); C07D 405/10 (2013.01);
Abstract

We describe ultra-short, short, and intermediate duration neuromuscular blocking compounds, reversible by cysteine or similar compounds, that are bisquaternary diesters of chlorofumaric, fumaric, or maleic acids where the quaternary groups are very different, creating a highly asymmetrical molecule where one quaternary includes an isoquinolinium ring system and the other includes a morpholinium, piperidinium, piperazinium, or pyrrolidinium system, pharmaceutical compositions, methods to use such compounds and compositions, and kits.

Find Patent Forward Citations

Savarese, John. (2015). Asymmetrical reversible neuromuscular blocking agents of ultra-short, short, or intermediate duration (U.S. Patent No. 9156826). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9156826

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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