The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 13, 2015
Filed:
Mar. 31, 2014
Applicant:
Ohio State Innovation Foundation, Columbus, OH (US);
Inventors:
Ching-Shih Chen, Upper Arlington, OH (US);
Matthew David Ringel, Columbus, OH (US);
Motoyashi Saji, Dublin, OH (US);
Yihui Ma, Zhenghou, CN;
Assignee:
Ohio State Innovation Foundation, Columbus, OH (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/415 (2006.01); C07D 231/12 (2006.01); C07D 231/14 (2006.01);
U.S. Cl.
CPC ...
C07D 231/12 (2013.01); A61K 31/415 (2013.01); C07D 231/14 (2013.01);
Abstract
Compounds according to formula I: wherein Ar is a fused aryl group, Ris selected from alkyl and aryl amides, CF, and CHOH, and Ris selected from hydrogen, —C(═O)CHNH, and —C(═O)CHCHNHare described. The compounds are effective for inhibiting p21-activated kinases, and can be used for prevention and treatment of cancer.