The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 13, 2015

Filed:

Feb. 20, 2010
Applicants:

Takao Hamakubo, Tokyo, JP;

Yasuhiro Mochizuki, Tokyo, JP;

Hiroyuki Aburatani, Tokyo, JP;

Hiroko Iwanari, Tokyo, JP;

Shunsuke Niwa, Tokyo, JP;

Yoshiko Nakada, Tokyo, JP;

Inventors:

Takao Hamakubo, Tokyo, JP;

Yasuhiro Mochizuki, Tokyo, JP;

Hiroyuki Aburatani, Tokyo, JP;

Hiroko Iwanari, Tokyo, JP;

Shunsuke Niwa, Tokyo, JP;

Yoshiko Nakada, Tokyo, JP;

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/30 (2006.01); C12N 5/24 (2006.01); G01N 33/574 (2006.01); G01N 33/577 (2006.01); A61K 51/10 (2006.01); A61K 39/00 (2006.01); G01N 33/53 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 51/1072 (2013.01); A61K 39/00 (2013.01); A61K 51/106 (2013.01); A61K 51/1054 (2013.01); A61K 51/1057 (2013.01); A61K 51/1063 (2013.01); A61K 51/1066 (2013.01); C07K 16/28 (2013.01); C07K 16/30 (2013.01); G01N 33/53 (2013.01); C07K 2317/34 (2013.01); C07K 2317/732 (2013.01); G01N 33/574 (2013.01);
Abstract

[Theme] To provide a monoclonal antibody against human GPR87. Also, to provide a novel means for diagnosing or treating a malignant tumor. [Solution means] Monoclonal antibodies against human GPR87 are provided. The antibodies can recognize human GPR87, which is expressed on a cell membrane while retaining a three-dimensional structure, and can recognize GPR87, which is expressed in a cell endogenously with an epitope being present in an extracellular domain of full-length human GPR87. The antibodies are thus useful in biochemical analysis, etc., of GPR87, useful in immunohistological diagnosis, etc., of squamous cell carcinoma, and also potentially useful in PET diagnosis, antibodies for treatment, etc., of squamous cell carcinoma.


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