The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 13, 2015
Filed:
May. 27, 2010
Applicant:
Richard H. Weisbart, Los Angeles, CA (US);
Inventor:
Richard H. Weisbart, Los Angeles, CA (US);
Assignee:
The United States Government as Represented by the Department of Veterans Affairs, Washington, DC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/48 (2006.01); C07K 16/44 (2006.01); C12N 15/62 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48538 (2013.01); A61K 47/48415 (2013.01); C07K 16/44 (2013.01); C12N 15/625 (2013.01); C07K 2317/77 (2013.01); C07K 2319/02 (2013.01); C07K 2319/036 (2013.01); C07K 2319/21 (2013.01); C07K 2319/41 (2013.01);
Abstract
The present invention provides peptide conjugates having improved solubility as well as increased secretion during cell based production, as well as methods of utilizing such peptides. The peptide conjugates include a short peptide domain defined by the amino acid sequence AGIH (SEQ ID NO: 8) and may include a biologically active molecule useful in intracellular and intranuclear transport of the biologically active molecule to treat various disorders and diseases.