The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 13, 2015
Filed:
Jun. 28, 2012
Applicants:
Xingli Meng, Allen, TX (US);
Raphael Schiffmann, Rockwall, TX (US);
Jinsong Shen, Allen, TX (US);
Inventors:
Assignee:
Baylor Research Institute, Dallas, TX (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61P 9/10 (2006.01); A61P 7/04 (2006.01); C12Q 1/68 (2006.01); A61P 25/00 (2006.01); C12N 5/077 (2010.01); C12Q 1/02 (2006.01); G01N 33/566 (2006.01); A61K 35/34 (2015.01); C12N 15/87 (2006.01); A61P 9/00 (2006.01); G01N 33/50 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
A61K 35/34 (2013.01); C12N 5/0657 (2013.01); G01N 33/5044 (2013.01); G01N 33/6893 (2013.01); C12N 2506/45 (2013.01); G01N 2800/32 (2013.01);
Abstract
A composition and method for generating patient- or person-specific proliferative and substantially pure cardiac myocyte cell lines from pluripotent stem cells (iPSCs) is described herein. The patient-specific cardiac myocyte cell lines of the present invention find applications in research, drug screening and autologous cell-based therapy. The method of the present invention is simple and reproducible and generates cardiac myocyte cells having high purities and proliferating capacities.