The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 13, 2015
Filed:
Oct. 29, 2013
Applicant:
Nnochiri Ekwuribe, Cary, NC (US);
Inventor:
Nnochiri Ekwuribe, Cary, NC (US);
Assignee:
Other;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/655 (2006.01); A61K 45/06 (2006.01); C07C 309/24 (2006.01); C07C 245/08 (2006.01); A01N 41/04 (2006.01); A01N 41/06 (2006.01); A01N 41/08 (2006.01); C07C 245/06 (2006.01); C07C 309/15 (2006.01); C07C 311/46 (2006.01); C07C 311/49 (2006.01); C07C 311/54 (2006.01); C07D 311/68 (2006.01);
U.S. Cl.
CPC ...
A61K 31/655 (2013.01); A01N 41/04 (2013.01); A01N 41/06 (2013.01); A01N 41/08 (2013.01); A61K 45/06 (2013.01); C07C 245/06 (2013.01); C07C 245/08 (2013.01); C07C 309/15 (2013.01); C07C 309/24 (2013.01); C07C 311/46 (2013.01); C07C 311/49 (2013.01); C07C 311/54 (2013.01); C07D 311/68 (2013.01);
Abstract
Prodrug compounds which metabolize into 5-ASA or analogs thereof, and taurine or analogs thereof, in the colon site are disclosed. Pharmaceutical compositions including the compounds, and methods of treatment using the compounds, are also disclosed. Such compounds have utility for treating or preventing gastrointestinal disorders, including colon cancer, ulcerative colitis and Crohn's disease.