The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 06, 2015

Filed:

Mar. 02, 2012
Applicants:

Christoph Boehm, Viernheim, DE;

Brigitte Niederberger, Olten, CH;

Rijk Edwin Oosterbroek, Cham, CH;

Susanne Wuerl, Mannheim, DE;

Inventors:

Christoph Boehm, Viernheim, DE;

Brigitte Niederberger, Olten, CH;

Rijk Edwin Oosterbroek, Cham, CH;

Susanne Wuerl, Mannheim, DE;

Assignee:

Roche Diagnostics Operations, Inc., Indianapolis, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); G01N 33/543 (2006.01); G01N 35/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/54366 (2013.01); B01L 3/502753 (2013.01); G01N 35/00069 (2013.01); B01L 2200/0631 (2013.01); B01L 2300/0806 (2013.01); B01L 2300/087 (2013.01); B01L 2300/0887 (2013.01); B01L 2400/0409 (2013.01);
Abstract

Method and system for carrying out heterogeneous chemical or biological reactions are disclosed. The method comprising providing an analytical device having at least one liquid processing unit having at least one reaction chamber and a first inlet channel in fluid communication with the reaction chamber. The method further comprises supplying to the reaction chamber via the first inlet channel or a second inlet channel analyte capturing particles, supplying to the reaction chamber via the first inlet channel or the second inlet channel a liquid sample containing an analyte of interest, and confining by an equilibrium of forces the analyte capturing particles in a particle rearrangement zone within the reaction chamber. The forces comprise a drag force Fd generated by flowing liquids and a counter-oriented force Fg. The method also comprises capturing analytes present in the liquid sample with the particles in the particle rearrangement zone.


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