The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 06, 2015

Filed:

Jan. 07, 2013
Applicant:

Ewha University-industry Collaboration Foundation, Seoul, KR;

Inventors:

Juyoung Yoon, Seoul, KR;

Guo Zhiqian, Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 31/22 (2006.01); G01N 31/00 (2006.01); C07D 403/08 (2006.01); C07D 403/02 (2006.01); C07D 209/14 (2006.01); G01N 33/84 (2006.01); C09B 23/01 (2006.01);
U.S. Cl.
CPC ...
G01N 31/221 (2013.01); C07D 209/14 (2013.01); C07D 403/08 (2013.01); C09B 23/0041 (2013.01); C09B 23/0066 (2013.01); G01N 33/84 (2013.01); Y10T 436/163333 (2015.01);
Abstract

The present invention relates to a novel cyanne derivative having a meso-reaction functional group in a polymethine chain, and a preparation method thereof, and the cyanine derivative having the reaction functional group substituted at the meso site may be suitable for mass production thanks to a very simple synthesis method, have a very fast reaction rate because while a related art reagent for detection of nerve agents undergoes two steps of reactions, the cyanine derivative of the present invention undergoes only one step of reaction, have very excellent sensitivity, and be useful as an acid pH-activated ratiometric NIR probe because it is able to be activated in an acidic pH and is usable in an aqueous environment.


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