The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 06, 2015

Filed:

Oct. 03, 2011
Applicants:

Juan G. Santiago, Stanford, CA (US);

Alexandre Persat, Metuchen, NJ (US);

Giancarlo Garcia, Stanford, CA (US);

Charbel Eid, Stanford, CA (US);

Inventors:

Juan G. Santiago, Stanford, CA (US);

Alexandre Persat, Metuchen, NJ (US);

Giancarlo Garcia, Stanford, CA (US);

Charbel Eid, Stanford, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/447 (2006.01);
U.S. Cl.
CPC ...
G01N 27/44795 (2013.01);
Abstract

Techniques for enhanced isotachophoresis assays using additives with spatial gradients include forming a concentration gradient of an additive along a channel from an input port to an output port. The channel is used for isotachophoresis with ions of a leading electrolyte having a first mobility greater than a mobility of an analyte, and ions of a trailing electrolyte having a second mobility less than the mobility of the analyte. The additive is different from both the leading electrolyte and the trailing electrolyte; and the additive has a third mobility that assures the analyte will encounter the additive. The method further comprises introducing a mixture of the trailing electrolyte and a sample including the analyte. The method further comprises applying an electric field to the channel; and, measuring the analyte.


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