The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 2015
Filed:
Dec. 08, 2010
Sun Kyu Lee, Gwangju, KR;
Sung Ki Nam, Gwangju, KR;
Su Heon Jeong, Gwangju, KR;
Jung Kyun Kim, Gwangju, KR;
DO Kyun Woo, Gwangju, KR;
Sung Yang, Gwangju, KR;
Sun Kyu Lee, Gwangju, KR;
Sung Ki Nam, Gwangju, KR;
Su Heon Jeong, Gwangju, KR;
Jung Kyun Kim, Gwangju, KR;
Do Kyun Woo, Gwangju, KR;
Sung Yang, Gwangju, KR;
Gwangju Institute of Science and Technology, Gwangju, KR;
Abstract
A sensor for measuring heat generated from cells, including a thermopile manufactured by surface-micromachining technology, and a microfluidic flow-channel structure for mixing cells with medium and dividing the mixture into cells and medium. Medium and cells are uniformly mixed using a micro-mixer. The mixture is separated into a medium microfluid and a cell microfluid using the Zweifach-Fung effect, after which signals measured in the two microfluids are amplified. The difference between the two signal values determines the amount of heat generated from the cells. The influence of noise caused by a change in external environment is eliminated. Convection heat dissipation caused by fluid flow is minimized. The sensor accurately measures the amount of heat generated from cells flowing in the microfluidic flow-channel. Diseases such as cancer are diagnosed using the difference between the measured amount of heat generated from cells and the standard amount of heat generated from normal cells.