The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 06, 2015

Filed:

Dec. 17, 2013
Applicant:

Life Technologies Corporation, Carlsbad, CA (US);

Inventors:

Rosaria Haugland, Eugene, OR (US);

Ching-Ying Cheung, San Ramon, CA (US);

Stephen Yue, Eugene, OR (US);

Assignee:

Life Technologies Corporation, Carlsbad, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/04 (2006.01); C07D 209/14 (2006.01); C12Q 1/68 (2006.01); C07D 209/12 (2006.01); C07D 209/24 (2006.01); C09B 23/12 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6876 (2013.01); C07D 209/12 (2013.01); C07D 209/14 (2013.01); C07D 209/24 (2013.01); C07D 401/04 (2013.01); C09B 23/12 (2013.01);
Abstract

The present invention provides methods and non-fluorescent carbocyanine quencher compounds having the general formula: Wherein the A moiety is a substituted pyridinium, unsubstituted pyridinium, substituted quinolinium, unsubstituted quinolinium, substituted benzazolium, unsubstituted benzazolium, substituted indolinium, or substituted indolinium. The invention further provides luminescent donor molecule-quencher pairs and luminescent donor molecule-quencher-luminescent acceptor molecule conjugates wherein the quencher is a cyanine compound of the present invention. The energy transfer pairs are used to detect an analyte of interest in a sample.


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