The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 2015
Filed:
May. 03, 2011
Applicants:
Masato Mitsuhashi, Irvine, CA (US);
Ernest C. Borden, Cleveland, OH (US);
Inventors:
Masato Mitsuhashi, Irvine, CA (US);
Ernest C. Borden, Cleveland, OH (US);
Assignees:
HITACHI CHEMICAL CO., LTD., Tokyo, JP;
HITACHI CHEMICAL COMPANY AMERICA, LTD, Cupertino, CA (US);
THE CLEVELAND CLINIC FOUNDATION, Cleveland, OH (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12Q 1/70 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6876 (2013.01); C12Q 1/6883 (2013.01); C12Q 1/6886 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/158 (2013.01);
Abstract
Embodiments of the invention relate generally to ex vivo methods of quantifying expression of interferon responsive genes and characterizing an individual's potential responsiveness to interferon administration. Certain embodiments relate to methods to monitor the efficacy of ongoing interferon therapy by evaluating expression of interferon responsive genes before and after interferon administration.