The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 2015
Filed:
May. 04, 2012
Daniel Müller, Hilden, DE;
Francesca Di Pasquale, Hilden, DE;
Daniel Müller, Hilden, DE;
Francesca Di Pasquale, Hilden, DE;
QIAGEN GMBH, Hilden, DE;
Abstract
The present application discloses a labeled nucleotide comprising a label attached via a linker, wherein said labeled nucleotide has the formula wherein Ris a residue with a negative net charge, preferably selected from the group consisting of a phosphate group, and a sulphate group; wherein R, Rand Rare independently selected from the group consisting of H, OH, and O; wherein 'n' is an integer between 0 and 16; wherein 'a' is an integer between 1 and 10; wherein SP is absent or a spacer; wherein X is said label; and wherein Y is a nucleotide or nucleoside. Furthermore, oligonucleotides comprising a labeled nucleotide according to the present invention and the use as a primer in amplification based methods is disclosed herein.