The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 06, 2015

Filed:

Apr. 06, 2012
Applicants:

Ole Thastrup, Birkerod, DK;

Morten Meldal, Copenhagen Nv, DK;

Grith Hagel, Dragor, DK;

Jens Chr. Norrild, Birkerod, DK;

Morten Hentzer, Holbæk, DK;

Inventors:

Ole Thastrup, Birkerod, DK;

Morten Meldal, Copenhagen Nv, DK;

Grith Hagel, Dragor, DK;

Jens Chr. Norrild, Birkerod, DK;

Morten Hentzer, Holbæk, DK;

Assignee:

2cureX, Birkerod, DK;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C40B 30/06 (2006.01); C12Q 1/02 (2006.01); C07K 1/04 (2006.01); C07K 5/103 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); G01N 33/50 (2006.01); G01N 33/543 (2006.01); G01N 33/68 (2006.01); G01N 35/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/025 (2013.01); C07K 1/047 (2013.01); C07K 5/1008 (2013.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01); G01N 33/5023 (2013.01); G01N 33/54313 (2013.01); G01N 33/6845 (2013.01); C40B 30/06 (2013.01); G01N 2035/00158 (2013.01); G01N 2500/10 (2013.01);
Abstract

The present invention relates to methods for identifying compounds capable of modulating a cellular response. The methods involve attaching living cells to solid supports comprising a library of test compounds. The test compounds are linked to the solid support via cleavable linkers and may thus be released from the solid supports. Solid supports comprising cells, wherein the cellular response of interest has been modulated are selected and the test compound of the solid support can then be identified. The cellular response may for example be changes in complex formation between proteins.


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