The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 06, 2015

Filed:

Mar. 08, 2012
Applicants:

David Ross Nielsen, Tempe, AZ (US);

Rebekah Mckenna, Mesa, AZ (US);

Inventors:

David Ross Nielsen, Tempe, AZ (US);

Rebekah McKenna, Mesa, AZ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 1/21 (2006.01); C12N 15/60 (2006.01); C12P 5/00 (2006.01); C12P 1/04 (2006.01); C12N 9/02 (2006.01); C12N 9/88 (2006.01); C12P 17/02 (2006.01);
U.S. Cl.
CPC ...
C12P 5/005 (2013.01); C12N 9/0071 (2013.01); C12N 9/88 (2013.01); C12P 1/04 (2013.01); C12P 17/02 (2013.01);
Abstract

A method for the in vivo production of styrene from renewable substrates using a recombinant microorganism is disclosed. Additionally, a method for the in vivo production of styrene oxide from renewable substrates using a recombinant microorganism is also disclosed. In both cases, the host cell expresses at least one gene encoding a polypeptide that possesses phenylalanine ammonia lyase activity in addition to at least one gene encoding a polypeptide that possesses trans-cinnamic acid decarboxylase activity. In the case of styrene oxide, the host cell must additionally express at least one gene encoding a polypeptide that possesses styrene monooxygenase activity.


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