The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 2015
Filed:
Aug. 27, 2012
Ahmed Kamal, Hyderabad, IN;
Rohini Khanna, Hyderabad, IN;
Chityal Ganesh Kumar, Hyderabad, IN;
Anver Basha Shaik, Hyderabad, IN;
Matam Shiva Kumar, Hyderabad, IN;
Ahmed Kamal, Hyderabad, IN;
Rohini Khanna, Hyderabad, IN;
Chityal Ganesh Kumar, Hyderabad, IN;
Anver Basha Shaik, Hyderabad, IN;
Matam Shiva Kumar, Hyderabad, IN;
COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH, New Delhi, IN;
Abstract
The present invention relates to a novel epoxide hydrolase enzyme which aims to achieve a high degree of resolution towards a broader range of substrates with high enantioselectivity and yields with minimal product inhibition. The invention further relates to a new bacterial strainsp. MTCC 5605 isolated from a petroleum-contaminated sludge sample, capable of producing the said enzyme. It is notable that the enzyme can be used as whole bacterial cell preparation, which allows continuous hydrolysis of substrates at even higher concentration and have an advantage of being recycled. The invention further relates to a process for the hydrolysis of different aryl epoxides which are potential synthons of intermediates for the synthesis of chiral amino alcohols and bioactive compounds like β-blockers.