The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 06, 2015

Filed:

May. 08, 2007
Applicants:

Bruce Kenknight, Maple Grove, MN (US);

Steven D. Girouard, Chagrin Falls, OH (US);

Inventors:

Bruce KenKnight, Maple Grove, MN (US);

Steven D. Girouard, Chagrin Falls, OH (US);

Assignee:

Cardiac Pacemakers, Inc., St. Paul, MN (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 13/00 (2006.01); A61N 1/362 (2006.01); C12N 5/077 (2010.01); A61K 35/12 (2015.01); A61M 37/00 (2006.01); A61B 17/34 (2006.01); A61B 17/00 (2006.01); A61B 18/00 (2006.01); A61N 1/32 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0657 (2013.01); A61K 35/12 (2013.01); A61M 37/0069 (2013.01); A61N 1/362 (2013.01); A61B 17/3468 (2013.01); A61B 2017/00247 (2013.01); A61B 2017/00256 (2013.01); A61B 2018/00392 (2013.01); A61N 1/326 (2013.01);
Abstract

A system is provided for stimulating one or more cells, wherein the stimulation is sub-threshold and may alter a transmembrane potential of the one or more cells. For some populations of cells it may be possible to affect the transmembrane potential to gain a therapeutic benefit. Cells of the sino-atrial node spontaneously depolarize predominantly due to the slow depolarization of transmembrane potential. The present system may provide sino-atrial cells with a local field stimulation that while not eliciting an action potential may nonetheless alter local transmembrane potential. Such alteration of transmembrane potential may permit an increase or decrease in a rate of depolarization, and hence modify heart rate.


Find Patent Forward Citations

Loading…