The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 2015
Filed:
Aug. 30, 2011
Applicants:
Han-chung Wu, Taipei, TW;
Ruei-min LU, Sanchong, TW;
Inventors:
Han-Chung Wu, Taipei, TW;
Ruei-Min Lu, Sanchong, TW;
Assignees:
ACADEMIA SINICA, Nankang, Taipei, TW;
Other;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 9/127 (2006.01); A61K 47/48 (2006.01); A61K 49/00 (2006.01); A61K 9/00 (2006.01); A61K 47/24 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2869 (2013.01); A61K 9/0019 (2013.01); A61K 9/1271 (2013.01); A61K 47/24 (2013.01); A61K 47/48823 (2013.01); A61K 49/0058 (2013.01); A61K 49/0067 (2013.01); C07K 16/2863 (2013.01); A61K 2039/505 (2013.01); C07K 2317/622 (2013.01); C07K 2317/77 (2013.01); C07K 2317/92 (2013.01); C07K 2319/30 (2013.01);
Abstract
Antibodies that bind to c-Met are provided herein, as well as related compositions and methods of use. Methods of use encompass cancer therapies and diagnostics. In certain embodiments, antibodies bind mammalian cell surface antigen (e.g., cancer cell surface antigen). The antibodies can also be endocytosed upon binding to cells. Cells that can be targeted by the antibodies include carcinomas, such as those in lung, kidney, liver, stomach, breast, and brain, etc.