The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 2015
Filed:
Feb. 14, 2008
Applicants:
Li-fang Liang, Savage, MD (US);
Stavros Topouzis, Seattle, WA (US);
Inventors:
Gideon Strassmann, Washington, DC (US);
Li-Fang Liang, Savage, MD (US);
Stavros Topouzis, Seattle, WA (US);
Assignee:
Scidera, Inc., Canton, OH (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 39/00 (2006.01); A61K 31/7105 (2006.01); C07K 16/22 (2006.01); C07K 16/18 (2006.01); A61K 38/18 (2006.01);
U.S. Cl.
CPC ...
C07K 16/22 (2013.01); A61K 38/1841 (2013.01); C07K 16/18 (2013.01); A61K 2039/505 (2013.01); Y10S 514/866 (2013.01);
Abstract
Methods for treating diabetes by administering an inhibitor of GDF-8, or a related member of Transforming Growth Factor-beta (TGF-β) superfamily of structurally-related growth factors (e.g., GDF-11) are disclosed. Also disclosed are methods for upregulating expression of hexose transporters, such as GLUT4 and GLUT1, in a subject by administering an inhibitor of GDF-8. Also disclosed are methods for increasing glucose uptake by cells in a subject, by administering an inhibitor of GDF-8.