The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 06, 2015
Filed:
Jul. 29, 2011
Gianluca Moroncini, Senigallia, IT;
Ada Funaro, Turin, IT;
Armando Gabrielli, Ancona, IT;
Vittorio Enrico Avvedimento, Caserta, IT;
Silvia Svegliati Baroni, Ancona, IT;
Mariarosaria Santillo, Naples, IT;
Roberto Paterno′, Naples, IT;
Gianluca Moroncini, Senigallia, IT;
Ada Funaro, Turin, IT;
Armando Gabrielli, Ancona, IT;
Vittorio Enrico Avvedimento, Caserta, IT;
Silvia Svegliati Baroni, Ancona, IT;
Mariarosaria Santillo, Naples, IT;
Roberto Paterno′, Naples, IT;
Other;
Abstract
The present invention refers to peptides comprised in the extracellular region of human PDGF receptor (hPDGFR) alpha, their use for detecting auto-antibodies anti-hPDGFR alpha and to a method for the diagnosis or the monitoring control for therapy of SSc. The present invention also refers to antibodies or recombinant or synthetic derivatives thereof able to recognize and bind to the above peptide and to their use in the treatment of SSc.