The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 06, 2015

Filed:

Aug. 03, 2009
Applicants:

Kang-yell Choi, Seoul, KR;

Hyun-yi Kim, Seoul, KR;

Ju-yong Yoon, Seoul, KR;

Inventors:

Kang-Yell Choi, Seoul, KR;

Hyun-Yi Kim, Seoul, KR;

Ju-Yong Yoon, Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/10 (2006.01); A61K 38/17 (2006.01); C07K 7/08 (2006.01); C07K 14/435 (2006.01); C07K 19/00 (2006.01); C07K 14/47 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4703 (2013.01); A61K 38/10 (2013.01); A61K 38/1709 (2013.01); C07K 7/08 (2013.01); A61K 47/48246 (2013.01); A61K 47/48315 (2013.01); C07K 2319/10 (2013.01);
Abstract

There are provided Idbf (inhibitor of Dvl and bone formation) which is a novel Dvl-binding protein that binds to Dvl to inhibit signal transduction carried out through the Wnt/β-catenin signaling pathway, a gene for coding for the same, the use thereof, and the use of an inhibitor of the Idbf. The Idbf was known to be expressed by activation of the Wnt/β-catenin signaling pathway and bind to Dvl to block signal transduction carried out through the Wnt/β-catenin signaling pathway. Therefore, the Idbf can be used in development of medicines for inhibiting the signal transduction carried out through the Wnt/β-catenin signaling pathway, and an Idbf inhibitor can be used in preparation of medicines for activating the signal transduction carried out through the Wnt/β-catenin signaling pathway.


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