The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 06, 2015

Filed:

Apr. 11, 2012
Applicants:

Vinay Girijavallabhan, Whippany, NJ (US);

F. George Njoroge, Carmel, IN (US);

Stephane Bogen, Somerset, NJ (US);

Angela Kerekes, Plainfield, NJ (US);

Frank Bennett, Cranford, NJ (US);

Ying Huang, Berkeley Heights, NJ (US);

Latha Nair, Edison, NJ (US);

Dmitri Pissarnitski, Scotch Plains, NJ (US);

Vishal Verma, San Francisco, CA (US);

Qun Dang, Westfield, NJ (US);

Ian Davies, Princeton, NJ (US);

David B. Olsen, Lansdale, PA (US);

Andrew Stamford, Chatham, NJ (US);

Joseph P. Vacca, Telford, PA (US);

Inventors:

Vinay Girijavallabhan, Whippany, NJ (US);

F. George Njoroge, Carmel, IN (US);

Stephane Bogen, Somerset, NJ (US);

Angela Kerekes, Plainfield, NJ (US);

Frank Bennett, Cranford, NJ (US);

Ying Huang, Berkeley Heights, NJ (US);

Latha Nair, Edison, NJ (US);

Dmitri Pissarnitski, Scotch Plains, NJ (US);

Vishal Verma, San Francisco, CA (US);

Qun Dang, Westfield, NJ (US);

Ian Davies, Princeton, NJ (US);

David B. Olsen, Lansdale, PA (US);

Andrew Stamford, Chatham, NJ (US);

Joseph P. Vacca, Telford, PA (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/06 (2006.01); C07H 19/20 (2006.01); C07H 19/10 (2006.01); C07H 19/12 (2006.01); C07H 19/16 (2006.01); C07H 19/04 (2006.01); C07H 19/207 (2006.01); C07H 19/11 (2006.01); C07H 19/213 (2006.01); A61K 31/7056 (2006.01); A61K 31/7068 (2006.01); A61K 31/7076 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07H 19/16 (2013.01); A61K 31/7056 (2013.01); A61K 31/7068 (2013.01); A61K 31/7076 (2013.01); A61K 45/06 (2013.01); C07H 19/06 (2013.01); C07H 19/10 (2013.01); C07H 19/11 (2013.01); C07H 19/20 (2013.01); C07H 19/207 (2013.01); C07H 19/213 (2013.01);
Abstract

The present invention relates to 2'-Cyano Substituted Nucleoside Derivatives of Formula (I): and pharmaceutically acceptable salts thereof, wherein B, X, R, Rand Rare as defined herein. The present invention also relates to compositions comprising at least one 2′-Cyano Substituted Nucleoside Derivative, and methods of using the 2′-Cyano Substituted Nucleoside Derivatives for treating or preventing HCV infection in a patient.


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