The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 06, 2015

Filed:

Mar. 15, 2012
Applicants:

Pascale A. J. Pouzet, Biberach an der Riss, DE;

Peter Nickolaus, Warthausen, DE;

Ulrike Werthmann, Biberach an der Riss, DE;

Rogelio P. Frutos, Sandy Hook, CT (US);

Bing-shiou Yang, Southbury, CT (US);

Soojin Kim, Demarest, NJ (US);

Jason Alan Mulder, New Milford, CT (US);

Nitinchandra Patel, Danbury, CT (US);

Chris H. Senanayake, Brookfield, CT (US);

Thomas G. Tampone, Southbury, CT (US);

Xudong Wei, Ridgefield, CT (US);

Inventors:

Pascale A. J. Pouzet, Biberach an der Riss, DE;

Peter Nickolaus, Warthausen, DE;

Ulrike Werthmann, Biberach an der Riss, DE;

Rogelio P. Frutos, Sandy Hook, CT (US);

Bing-Shiou Yang, Southbury, CT (US);

Soojin Kim, Demarest, NJ (US);

Jason Alan Mulder, New Milford, CT (US);

Nitinchandra Patel, Danbury, CT (US);

Chris H. Senanayake, Brookfield, CT (US);

Thomas G. Tampone, Southbury, CT (US);

Xudong Wei, Ridgefield, CT (US);

Assignee:

Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/02 (2006.01); C07D 495/04 (2006.01); C07D 401/04 (2006.01); C07C 213/00 (2006.01); A61K 31/519 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 495/04 (2013.01); A61K 31/519 (2013.01); A61K 45/06 (2013.01); C07C 213/00 (2013.01); C07D 401/04 (2013.01); C07B 2200/13 (2013.01);
Abstract

The invention relates to novel piperidino-dihydrothienopyrimidine sulfoxides of formula I, wherein Ring A is a 6-membered aromatic ring which may optionally comprise one or two nitrogen atoms andwherein R is Cl andwherein R may be located either in the para-, meta- or ortho-position of Ring A,wherein S* is a sulphur atom that represents a chiral center,and all pharmaceutically acceptable salts, enantiomers and racemates, hydrates and solvates thereof and the use of these compounds for the treatment of inflammatory or allergic diseases of the respiratory tract such as COPD or asthma.


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